The major objection to the universality argument stems from a vast movement that has arisen just since the turn of the century, the rapidly expanding field of Neuro-theology (or Cognative Science of Religion):
In recent years a number of books have been published in the United States which argue that religious experiences and activities can be measured as neural activity in the brain...these theories purport to explain why there are common patterns of religious behavior and experience across culture which are observable in the field of comparative religion..Most such theories assert that as our understanding the brains activities develop through exploration of its underlying structures and mechanisms so the origin of religious experiences and ritual behavior will be revealed...These theorioes purport to explain why there are common paterns of religious behaviors and experience across cultures.
R. Joseph states, “that The brain underlies all experience of living human beings is an absolute statement It subsumes all religious phenomena and all mystical experiences including hyper lucid visionary experiences, trance states, contemplating God and the experience of unitary absorption.” Since religious experience is linked to brain chemistry it must be the result of brain chemistry, thus there’s no reason to assume it’s indicative of any sort of supernatural causation. This view has become standard in the scientific community. Tiger and McGuire state:
Religion as a process generates remarkable action, countless events, numberless provocative artifacts. Yet what factual phenomenon except perhaps slips of ancient holy paper underlies and animates one of the most influential and durable of human endeavors? We've an answer. Shivers in the moist tissue of the brain confect cathedrals our proposal is that all religions differ but all share two destinies: they are the product of the human brain. They endure because of the strong influence of the product of the human brain. The brain is a sturdy organ ith common characteristics everywhere. A neurosurgeon can work confidently on a vatican patient and another in mecca. Same tissue, same mechinisms. One such mechinnism is a readiness to generate religions.
Skeptics argue that the experiences have a commonality because they are all produced by human brain structure. In other words the names from the various religions are the constructs but the experiences that unite the subjects and that transcend the individual cultural filters are the same because they are products of a shared structure that of the human brain. Ilkka Pyysiäinen and Marc Hauser state the argument:
Considerable debate has surrounded the question of the origins and evolution of religion. One proposal views religion as an adaptation for cooperation, whereas an alternative proposal views religion as a by-product of evolved, non-religious, cognitive functions. We critically evaluate each approach, explore the link between religion and morality in particular, and argue that recent empirical work in moral psychology provides stronger support for the by-product approach. Specifically, despite differences in religious background, individuals show no difference in the pattern of their moral judgments for unfamiliar moral scenarios. These findings suggest that religion evolved from pre-existing cognitive functions, but that it may then have been subject to selection, creating an adaptively designed system for solving the problem of cooperation.
In other words, the discussion about origins of religion there are two genetic choices, a specific gene, or spandrels. The weight of the evidence, according to Pyysiäinen and Marc Hauser, leans toward the latter (spandrels: pre-existing cognitive functions based upon combined genetic functions from other areas). The deeper level of complexity comes with the finding that religion evolved from spandrels and yet it is still subject to adaptation manifesting in a system for cooperation (religion). What their findings really suggest is that moral motions are more basic than religious doctrine and that moral decision making transcends social structure or organization. Religion is perpetuated because its conducive to cooperation but there is an underlying sense or moral motion that's tied to the specific religious affiliation. Moral reasoning is not the same as mystical experience. Religious experience is a passive apprehension and moral decision making is an active use of deductive reasoning. Moreover, in finding religion is not original adaptation they are really negating the brain structure argument for uniformity of religious experiences. Their findings show that moral decisions transcended the religious background, thus the religious symbols, ideas, and presumably experiences are not reducible to moral motions since the latter transcends the former. If religious experiences are of the same nature because of the state of human brain structure we should expect to find a conformation between moral motions religious experience. Frederick Schleiermacher argued that religious religion is more than just enhanced ethical thinking. This has led to the widely accepted theory of the religious a priori. Religion is understood as it's on discipline separate from ethics. The a priori is seen as a “special for of awareness which exists alongside the cognitive, moral and aesthetic forms of awareness and is not explicable by reference to them.” 
As an argument about the origin of religion, the genetic aspects would only be the proximate cause. It doesn't rule out a distal cause in the divine. As an argument about the origin of religion, the genetic aspects would only be the proximate cause. It doesn't rule out a distal cause in the divine. Andrew Newberg, one of the pioneers in researching neural activity of religious experience and God talk tells us that none of the research disproves God, nor could it:
…Tracing spiritual experience to neurological behavior does not disprove its realness. If God does exist, for example, and if He appeared to you in some incarnation, you would have no way of experiencing His presence, except as part of a neurologically generated rendition of reality. You would need auditory processing to hear his voice, visual processing to see His face, and cognitive processing to make sense of his message. Even if he spoke to you mystically, without words, you would need cognitive functions to comprehend his meaning, and input form the brain’s emotional centers to fill you with rapture and awe. Neurology makes it clear: there is no other way for God to get into your head except through the brain’s neural pathways. Correspondingly, God cannot exist as a concept or as reality anyplace else but in your mind. In this sense, both spiritual experiences and experiences of a more ordinary material nature are made real to the mind in the very same way—through the processing powers of the brain and the cognitive functions of the mind. Whatever the ultimate nature of spiritual experience might be—weather it is in fact an actual perception of spiritual reality—or merely an interpretation of sheer neurological function—all that is meaningful in human spirituality happens in the mind. In other words, the mind is mystical by default.
Just being connected to brain chemistry is not enough to disprove the universal experience argument.
The problem with the brain structure argument is that even though we all have human brain structure we don’t all have the same kinds of experiences. We can’t assume that universal experiences come from brain structure alone. First, not everyone has mystical experience. Even though the incidence rates are high they are not 100%. We all have human brain structure but not all have these experiences. Secondly, even among those who do there are varying degrees of the experience. William James saw it as a continuum and Robert Wuthnow, one of the early researchers who did a modern scientific study on the phenomenon also theorized that there is a continuum upon which degree of experience varies. If the brain structure argument was true then we should expect to always have the same experience; we should have the same culture. We have differing experiences and even our perceptions of the same phenomena vary. Yet the experience of mystical phenomena is not identical since it is filtered through cultural constructs and translated into the doctrinal understanding of traditions that the experiencers identify as their own.
The brain Structure argument is based upon the same premises reductionists take to the topic of consciousness and brain/mind. They assume that any subjective experience is ultimately the result of brain chemistry. There really is no reason to assume this other than the fact that brain chemistry plays a role in our perceptions. There’s no basis for the assumption that any mental phenomena must originate in brain chemistry alone. In those arguments a sense usually emerges that any involvement with the natural cancels the supernatural. I suggest that this is the ersatz version of supernature. The alien realm, juxtaposed to the natural realm and brought in as a counter to naturalism, this is the false concept of Supernatural that Eugene R, Fairweather spoke about. The original concept of supernature is that of the ground and end of the natural. Thus it would be involved with nature. The ground/end of nature is the ontology of supernature and pragmatic working out of the phenomenon would be the power of God to lift human nature to a higher level, as discussed by Fairweather and aslo Mathias Joseph Scheeben. How can human nature be elevated without supernature being involved with the realm of nature? Thus, if it is true that bonafide experiences of God are mediated by brain chemistry, then the fact that supernature works through evolutionary processes and physiological realities such as brain chemistry is hardly surprising.
Some studies have explored questions about brain function and the texture or mechanics of mystical experience. Van Elk et al explore the hypothesis that the sensation of supernatural presence is an adaptation from the need to over-detect presences of predictors in the jungle. There findings did not coroborate that hypothesis. He does makes the statement that it otherwise lacks empirical proof. In other words if one sets out on a jungle trail, and there is darkness, sensing a predictor and turning back from the trek would be helpful. If the sensation was wrong and there was no predictor the mistake of being wrong would be less graven that of being right but ignoring the sense. Thus, the sensation of presence is selected for. This might be used by a skeptic to answer the argument from mystical experience. Elk has five experiments that that seek to explore weather processing concepts about supernatural agents enhances detection in the environment.
Participants were presented with point light stimuli representing kinds of biological motion, or with pictures of faces embedded in a noise mask. Participants were asked to indicate if the stimuli represented a human agent or not. In each case they used three “primes,” one for supernatural, one ofr human, one for animal. They found that supernatural primes facilitated better agent detection. So the argument is that the perceived presence of agents in threatening situations and tendencies to anthropomorphizing leads stronger belief in ghosts, demons, angels, gods and other “supernatural” agency. They point to a body of work consisting of several studies showing that particular paranormal beliefs are a reliable predictor of illusory perceptions of faces and agency detection. These studies include Willard and Norenzayan (2013), Reikki et. al. (2013), and Petrican and Burris (2012). “although these studies provide tentative support for the relation between agency detection and supernatural beliefs, the notion that reigious beliefs are a byproduct of perceptual biases to detect patterns and agency has been challenge by several authors...” (Bulbulia, 2004, Lisdorf 2007, and McKay and Efferson, 2010).
While it may be true that some aspects of mystical experience are genetically related, and may be related to agent detection, that is no proof that mystical experience originates wholly within a naturalistic and genetic framework. First, because these studies only demonstrate a correlation between supernatural beliefs and agency detection. There is no attempt to establish the direction of a causal relationship. If there is a connection between supernatural and agent detection it could as easily be that awareness of supernatural concepts makes one more sensitive to agent detection. Secondly, of course just being genetically related doesn't reduce the phenomenon wholly to genetic endowments. Thirdly, there is a lot more to mystical experience than agent detection. Both involve sensing a presence beyond that point the differences are immense. I am not even sure that facial recognition and sensing a predator are similar enough to count for anything. In sensing being observed one is not usually aware of visual ques as one would be in facial recognition. There's no guarantee that the quality of the sensing is the same. Feeling the divine presence is much more august and involves levels and textures. Such an experience is, overall, positive, life changing, transformational (even noetic) but merely feeling one is being observed could be creepy, negative, or even trivial. The vast differences can be spelled out in the tiebreakers I discuss in The Trace of God.
If supernature manifests itself in the natural realm through brain chemistry then the conclusion that this is somehow indicative of the divine could go either way. We can’t rule out the divine or supernatural just because it involves the natural realm. What then is the real distinguishing feature that tells us this is inductive of something other than nature? That’s where I introduce the “tie breakers.” There are aspects of the situation that indicate the effects of having the experience could not be produced by nature unaided:
(1) The transformative effects
The experience is good for us. It changes the experiencer across the board. These effects are well documented by that huge body of empirical research. They include self actualization, therapeutic effects that actually enhance healing form mental problems, less depression better mental outlook and so on. Summarizing the results of two of the major studies:
This is not merely a list of warm fuzzies. The results represent actual life transformation and change of world view. The results are dramatic and positive; well grounded psychological health, a deep sense of meaning and purpose in life, overcoming fear of death and overcoming physical addictions. Examples, Patricia Ryan's study finds that abuse victims often come to view God in more cosmic and impersonal terms. Or they become embittered and turn away from God, victims of childhood trauma and abuse often report that they felt the abuser was trying to destroy their soul and that this was the one inviolable core that could not be destroyed. This sense was related to mystical experience. Loretta Do Rozario studied patients who were either dying or in chronic pain. She found that mystical experience elevated the sense of illness and pain to a level of the “universal search for meaning and self transcendence.” The subjects reported that the experience ot only enabled them to cope with pain and fear of death but also enabled them to experience joy within the hardship.
Skeptics often advance the placebo argument, but it is neutralized because Placebos require expectation and a large portion of mystical experience is not expected. It’s not something people usually set out to have. Without being able to argue for placebo effect there is really no way to account for the transformational effects. Moreover, while placebo get's used against any claim about the mind there's actually a much more narrow range to which it rightly applies.
...People frequently expand the concept of the placebo effect very broady to include just about every conceivable sort of beneficial, biological, social or human interaction that doesn't involve some drug well known to the pharmacopeia. The concept of placebo has been expanded much more broadly than this. Some attribute the effects of various alternative medical systems such as homeopathy or chiropractic to placebo effect. Others have described studies that show the positive effects of enhanced communication, such as Egbert's as the ploaebo response without the placebo.
Thus the burden of proof is upon the skeptic to prove that placebo even applies to religious experience.
(2) Noetic aspects to the experiences
These are not informational but there is a sense in which the mystic feels that he has learned soemthing about the universe as a result of the experience. This usually is on the order of “God loves me” or “all is one.”
(3) The experience contains
the sense of the numinous or sense of the holy.
This is closely related to the Noetic sense and they clearly overlap but there is a distinction. The snse of the Holy could be more general and gives the sense that some unique and special aspect of reality exists. Some noetic qualities might be considered doctrinal in nature. “all is one” is a doctrinal statement. While I don't advocate using mystical experience to shape doctrine, because the shaping of doctrine in the Christian tradition revolves around pre given principles in revelatory texts, the nature of these qualities indicates more is going on than just misfire of some neuron.
(4) why positive?
These experiences are never negative. The only negativity associated with mystical experience is the sense of the mysterium tremendum, the highly serious nature of the Holy. That is not a lasting negative effect. If this is nothing more than brain chemistry and it’s just some sort of misfire where the brain just forgets to connect the sense of self to the part that says “I am not the world,” why is it so positive, transformative, vital? It’s not often that such a positive experience results form a biological accident.
(5) bad evolutionary theory
Mystical experience has not been tied to gene frequency. So the argument about adaptation has to rest upon the intermediaries that it provides, such as surviving long winters so one can have gene frequency. Yet all of those kinds of experiences flaunt the explanatory gap of consciousness. Why should we develop a mystically based sense of the world to get through hard long winter when we could more easily develop a brain circuiting that ignores boredom? Then this adaptation that is only there because it enabled us to get through being snowed in has such an amazing array of other effects such as life transformation and better mental health, and leads to the development of such complex fantasisms of errors as religious belief and organized religion. It’s so inefficient. Surely survival of the fittest should take the course of least resistance?
(6) Navigation in life
Mystical experiences enable navigation in life, these experiences and their effects enable us to get through and to set our sights on higher idealistic concepts and ways of life. They provide a sense of self actualization, authentication, and enable the subjects to bear up in the face of adversity. Rozario writes about those in her study who suffered chronic pain or were dying: “The inner awareness of wholeness despite the odds points to an explicit experience of life which can transcend form and matter. This experience of wholeness or consciousness extends and challenges the view of disability and illness as only a myth making and revaluing opportunity in the lives of people.” Gackenback, writes:
These states of being also result in behavioral and health changes. Ludwig (1985) found that 14% of people claiming spontaneous remission from alcoholism was due to mystical experiences while Richards (1978) found with cancer patients treated in a hallucinogenic drug-assisted therapy who reported mystical experiences improved significantly more on a measure of self-actualization than those who also had the drug but did not have a mystical experience. In terms of the Vedic Psychology group they report a wide range of positive behavioral results from the practice of meditation and as outlined above go to great pains to show that it is the transcendence aspect of that practice that is primarily responsible for the changes. Thus improved performance in many areas of society have been reported including education and business as well as personal health states (reviewed and summarized in Alexander et al., 1990). Specifically, the Vedic Psychology group have found that mystical experiences were associated with "refined sensory threshold and enhanced mind-body coordination (p. 115; Alexander et al., 1987).
 George D. Chryssides and Ron Geives, The Study of Religion an Introduction to key ideas and methods. London, New Deli, New york: Bloomsbury, 2nd ed. 2007, 59-60.
Chryssides is a research fellow with the University of Birmingham. He has an MA in Philosophy and D Phil in systematic theology from University of Glasgow. Among the books he mentions as examples of the trend are Why God Wont Go Away, by E. Aquili andAndrew Newberg (1999) , and Nuero-Theology by R. Joseph (2003)
 R. Joseph, Nuero-Theology:Brain, Science, Spirituality, Religious Experience. University Pr; 2nd edition (May 15, 2003) 22.
Lionel Tiger and Michael McGuire, God's Brain, Amherst, New York: Prometheus Books, 2010. 11.
Adrian Hastings, Alistair Mason, Hugh S. Pyper. The Oxford Companion to Christian Thought:Intellectual, Spiritual and Moral Horizons of Christianity, New York, NY: Oxford University Press, 2000, 483
In the Trace of God I do two chapters defending Schleiermacher's notion and the religious a priori against reductionist based attacks by philosopher yne Proudfoot. (Hinman, Trace...op. Cit., 179-241).
David Pailin, “The Religious a priori,” Westminster Dictionary of Christian Theology, Louisville Kentucky: Westminster John Knox Press, Alan Richardson and John Bowden, ed.,1983, 498.
Andrew Newberg, Why God Won’t God Away: Brain Science and the Biology of Belief. (New York, Ballentine Books), 2001, 37.
Eugene R. Fairweather, “Christianity and the Supernatural,” in New Theology no.1. New York: Macmillian, Martin E. Marty and Dean G. Peerman ed. 1964. 235-256
Mathias Joseph Scheeben in Fairweather, Ibid.
Michiel Elk, Bastiaan T. Rutjens, Joop van der Pligt,& Frenk van Harrveled (2016) Priming of Supernatural agent concepts and agency detection, Religion, Brain and Behavior, 6:1, 4-33, DOL: 10.1080/2153599X.2014.93344
Ibid., 5. A.K. Willard and A. Norenzayan, “Cognative Biases Explain Religious Belief and belief in life's purpose,” Cognition 129 (2013), 379-391. T. Reikki, M.Litterman, et. al. “Paranormal and religious believers are more prone to illusary face perception than skeptics and none believers.” applied cognitive psychology 27 (2013) 150-155, and R. Petrican and C.T. Burris, “Am I a Stone? Over attribution of agency and Religious Orientation,” Religion and Spirituality 4 (2012), 312-323.
Ibid., 6. J. Bulbulia, “The Cognitive and Evolutionary Psychology of Religion,” Biology and Philosophy 19, (2004) 655-686, A. Lisdorf, “What's HIDD'n in the HADD,” Journal of Cognition and Culture 7, (2007), 341-353, and R. McKay and C. Efferson, “Subtitles of Error Management,” Evolution and Human Behavior, 31 (5)(2010) 309-319.
Patricia L. Ryan, “Spirituality Among Adult Survivors of Childhood Violence: a Literary Review.” The Journal of Transpersonal Psychology, Vol. 30, no. 1, (1998) 43.
Loretta Do Rozario, “Spirituality in the Lives of People With Disability and Chronic Illness: A Creative Paradigm of Wholness and Reconstitution.” Disability and Rehabilitation: An International and Multidisciplinary Journal, Vol. 19, no. 10, (1997) 427.
Hinman, Trace...Op cit., 291.
Daiel E. Morman, ayne B. Jonas, “Deconstructing the Placebo Effect and Finding the Meaning Response.” Annuals of Internal Medicine, Vol. 136, issue 6, (19 March 2002), 471-476. Dr. Moreman is an anthropologist at University of Michigan.
Rozario, op.cit. 102.
Jayne Gackenback,Transpersonal Childhood Experiences of Higher States of Consciousness: Literature Review and Theoretical Integration. Unpublished paper (1992) Online resouirce
http://www.sawka.com/spiritwatch/cehsc/ipure.htm accessed 1/19/16.
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